Endocrine Abstracts

Background: Hypopituitary patients with untreated growth hormone deficiency (GHD) have increased fat mass, dyslipidaemia and insulin resistance. Inappropriately low thyroxine doses in patients with central hypothyroidism (CH) may also promote such clinical features.Objective: To examine metabolic outcome of thyroxine replacement in hypopituitary patients before and after GH replacement.Method: One thousand and six hundred and two p...

Background: The number of studies on the incidence of pituitary adenomas (PAs) is limited. The aim of this study was to evaluate the annual incidence of PAs in Västra Götaland, Sweden, with a targeted population of 1.6 million inhabitants.Patients and methods: Data from adult patients diagnosed with PA in 2001–2011, living in the Västra Götaland County, were collected from the Swedish Pituitary Registry (SPR). In addition, medica...

Introduction: Graves’ disease (GD) can negatively affect the quality of life. Research on GD in childhood, accounting for 1-5% of cases, has so far predominantly focused on treatment results. There is limited knowledge about association with other diseases and long-term psychosocial effects.Aims: We aimed to compare disease burden and psychosocial outcomes between childhood/young adult GD patients and unexposed population controls.<p class="abst...